| Lesion |
Clinical significance |
|
| Epithelial hyperplasia |
|
| Usual Type |
Follow up not appropriate |
|
| Lobular Neoplasia |
Risk factor |
| Atypical ductal hyperplasia |
Follow up only required |
| Ductal carcinoma in situ |
No specific therapy |
| Low grade < or = 3 mm |
|
|
| Low grade > 3 mm |
Excellent prognosis lesions |
| Intermediate grade |
Complete excision required |
| High grade |
|
| (Microinvasive carcinoma) |
+/- axillary dissection |
| « Small » invasive carcinomas |
+/- local irradiation |
| < 15 mm special type grade I |
no systemic therapy |
|
| Invasive carcinoma |
Local and systemic therapy based on evaluation of prognostic
factors |
