CLINICAL INFORMATION :

• 17 year-old girl
• HBs+ known since 1984 + cytolysis +++.
• Now : ALT : normal. No symptoms.

HISTOLOGY :

• 15 portal triads ==> OK
• Preserved lobular pattern, portal fibrosis with porto-portal tracts (Fig. 8-9)
• Viral B chronic hepatitis
  No activity
  Moderate portal fibrosis with porto-portal septa
  Metavir : A0 F3
• HbsAg, intracytoplasmic and membranous, (40 % H) (Fig. 10)
  HbcAg negative

==> " Hbcore free - HBs type "
  

fig. 8		fig. 9
fig. 10