CLINICAL INFORMATION :

36 year-old man. Serology HBV+ and HCV+. Biopsy before treatment.

HISTOLOGY :

• 12 portal triads ==> OK
• Preserved lobular pattern with porto-portal bridges (Fig. 11) and 1 porto-central bridge (Fig. 12)
• " Ground glass " hepatocytes (cf. intracytoplasmic HbsAg) (Fig.13)
• Viral B + C chronic hepatitis
  No activity
  Portal fibrosis with porto-portal and porto-central brigdes
  Metavir : A0 F2-3
• HbsAg cytoplasmic (80 H) (Fig. 14)
  Hbcore Ag negative

==> " Hbcore free - HBs type "

==> Etiology : rôle of virus C > virus B
  

fig. 11		fig. 12
fig. 13		fig. 14