CLINICAL INFORMATION :

61 year-old woman. HCV+. ANA+ (1/2500). ALT increased. Hemodialysis for nier insufficiency.

HISTOLOGY :

• 17 portal triads ==> OK
• Intralobular hepatocytes condensations (Fig. 18) + " piece meal necrosis " (Fig. 19)
• Preserved lobular pattern with portal fibrosis and some porto-portal brigdes (Fig. 20)
• Focal moderate macrovesicular steatosis
• Viral C chronic hepatitis
  Moderate activity
  Portal fibrosis with porto-portal bridges
  Metavir : A2 F3

NB: No histologic signs of autoimmunity : no severe activity, no plasmatocytes
      But negative histology can't exclude the role of autoimmunity.

fig. 18		fig. 19
fig. 20