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TABLE 4
| Nodules in FCL* | Reactive nodules | |||
| Size | usually large | usually small | ||
| Number | multiple | unique or multiple | ||
| Localization | paratrabecular | intertrabecular | ||
| Borders | not sharp | sharp | ||
| Germinal centers | usually absent | possible, unusual | ||
| IHC | usually B > T | usually B < T | ||
| FDC** | often present | unusual |
*FCL = Follicular Center Lymphoma
**FDC = Follicular Dendritic Cell.
No absolute criteria !
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